Article
Melting curve SNP (McSNP) genotyping: a useful approach for diallelic genotyping in forensic science.
Journal of forensic sciences - 1 May 2002
Ye Jian, Parra Esteban J, Sosnoski Donna M, Hiester Kevin, Underhill P A, Shriver Mark D
Abstract excerpt
The increasing availability of Single Nucleotide Polymorphisms (SNPs) and Deletion/Insertion Polymorphisms (DIPs), as well as the outstanding progress in SNP genotyping technologies, will impact forensics profoundly. We have developed a new method for genotyping SNPs and DIPs, which is based on the determination of melting curve profiles of amplified DNA in solution. We have termed this method Melting curve SNP...
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