Article
Isolation of a novel mouse variant of the drs tumor suppressor gene.
Cancer letters - 8 Sept 2002
Kawai Takao, Suzuki Yasuhiko, Yamashita Atsuko, Inoue Hirokazu
Abstract excerpt
The drs gene was isolated as a transformation suppressor against the v-src oncogene. Drs protein has a transmembrane domain and three consensus repeats (CRs) called Sushi motifs in the extracellular domain. The drs gene also has the ability to suppress anchorage-independent growth of human cancer cell lines. In this paper, we report the isolation of a novel variant cDNA of mouse drs (mDRS-2) containing two CRs,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
