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Identification and characterization of the murine ortholog <i>(brms1)</i> of breast‐cancer metastasis suppressor 1 <i>(BRMS1)</i>

4 Oct 2001

Abstract excerpt

We have cloned a novel metastasis-suppressor gene (BRMS1) by differential display, comparing metastatic human breast carcinoma cell line MDA-MB-435 to its metastasis-suppressed human chromosome 11 microcell hybrid. Screening of a murine cDNA library led to the identification of a 1.4 kb cDNA with a sequence revealing 85% homology to human BRMS1 within the open reading frame. The predicted protein sequence for the...

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PMID: 11774238
DOI: 10.1002/ijc.1569

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