Article
Suppression of anchorage-independent growth of human cancer cell lines by the drs gene.
Oncogene - 26 Aug 1999
Yamashita A, Hakura A, Inoue H
Abstract excerpt
We have previously reported that the drs gene, whose mRNA expression is downregulated by retroviral oncogenes such as v-src and v-K-ras, has the ability to suppress transformation by v-src in a rat cell line F2408. We have now isolated a human homolog of this gene (h-drs) and found that the expression of h-drs mRNA is markedly downregulated in a variety of human cancer cell lines including those of the colon,...
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