Article
GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination.
The Journal of biological chemistry - 20 Feb 2004
Shiba Yoko, Katoh Yohei, Shiba Tomoo, Yoshino Kaori, Takatsu Hiroyuki, Kobayashi Hiromi, Shin Hye-Won, Wakatsuki Soichi, Nakayama Kazuhisa
Abstract excerpt
GGAs (Golgi-localizing, gamma-adaptin ear domain homology, ADP-ribosylation factor (ARF)-binding proteins) are a family of monomeric adaptor proteins involved in membrane trafficking from the trans-Golgi network to endosomes. The GAT (GGA and Tom1) domains of GGAs have previously been shown to interact with GTP-bound ARF and to be crucial for membrane recruitment of GGAs. Here we show that the C-terminal...
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