Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel subtype of AP-1-binding motif within the palmitoylated trans-Golgi network/endosomal accessory protein Gadkin/gamma-BAR.

The Journal of biological chemistry - 5 Feb 2010

Maritzen Tanja, Schmidt Michael R, Kukhtina Viktoria, Higman Victoria A, Strauss Holger, Volkmer Rudolf, Oschkinat Hartmut, Dotti Carlos G, Haucke Volker

Abstract excerpt

Membrane traffic between the trans-Golgi network (TGN) and endosomes is mediated in part by the assembly of clathrin-AP-1 adaptor complex-coated vesicles. This process involves multiple accessory proteins that directly bind to the ear domain of AP-1gamma via degenerate peptide motifs that conform to the consensus sequence diameterG(P/D/E)(diameter/L/M) (with diameter being a large hydrophobic amino acid)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorocebus aethiops
Share to Circular Dichroism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endosomes

Share to Lipoylation

Share to Magnetic Resonance Spectroscopy

Share to Protein Interaction Domains and Motifs

Share to trans-Golgi Network

Share to Transcription Factor AP-1

Source

Open in PubMed Open full text

Identifiers

PMID: 19965873
DOI: 10.1074/jbc.M109.049197
PMCID: PMC2823548

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel subtype of AP-1-binding motif within the palmitoylated trans-Golgi network/endosomal accessory protein Gadkin/gamma-BAR.PMID 19965873Read ↗

Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain.Semantic proximity Read ↗

Endocytic Adaptor Proteins in Health and Disease: Lessons from Model Organisms and Human Mutations.Semantic proximity Read ↗

AAGAB is an assembly chaperone regulating AP1 and AP2 clathrin adaptorsSemantic proximity Read ↗

A hypomorphic mutation of the gamma-1 adaptin gene (Ap1g1) causes inner ear, retina, thyroid, and testes abnormalities in mice.Semantic proximity Read ↗

A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome.Semantic proximity Read ↗

GGA1 interacts with the adaptor protein AP-1 through a WNSF sequence in its hinge region.Semantic proximity Read ↗

Two WXXF-based motifs in NECAPs define the specificity of accessory protein binding to AP-1 and AP-2.Semantic proximity Read ↗

Palmitoylation of protease-activated receptor-1 regulates adaptor protein complex-2 and -3 interaction with tyrosine-based motifs and endocytic sorting.Semantic proximity Read ↗

Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi network.Semantic proximity Read ↗

Neuronal functions of adaptor complexes involved in protein sorting.Semantic proximity Read ↗

Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor.Semantic proximity Read ↗

Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.