Article
Phenotypic alterations and IL-1beta production in CD34(+) progenitor- and monocyte-derived dendritic cells after exposure to allergens: a comparative analysis.
Archives of dermatological research - 1 May 2002
De Smedt Ann C A, Van Den Heuvel Rosette L, Van Tendeloo Vigor F I, Berneman Zwi N, Schoeters Greet E R, Weber E, Tuschl H
Abstract excerpt
Dendritic cells (DC) have been shown to capture and process antigens and play an initiating role in contact sensitization. Cells with dendritic morphology can be generated in vitro either from CD34(+) cord blood cells or from CD14(+) peripheral monocytes. The aim of this study was to determine the state of maturation/activation of both populations after exposure to several concentrations of four well-established...
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