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Article

Moderate skin sensitizers can induce phenotypic changes on in vitro generated dendritic cells.

Toxicology in vitro : an international journal published in association with BIBRA - 1 Aug 2004

Staquet M J, Sportouch M, Jacquet C, Schmitt D, Guesnet J, Péguet-Navarro J

Abstract excerpt

In the present study, we analyzed the phenotypic alterations induced by several allergens on immature dendritic cells (DC), with the aim to develop a potential in vitro alternative for predicting the sensitizing potential of chemicals. DC were generated from human monocytes cultured in the presence of GM-CSF, IL-4 and TGF-beta1 and treated for 2 or 4 days with different chemicals. Surface marker expression...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15130607
DOI: 10.1016/j.tiv.2003.12.005

Genes

CCR7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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