Article
Adhesion of dendritic cells derived from CD34+ progenitors to resting human dermal microvascular endothelial cells is down-regulated upon maturation and partially depends on CD11a-CD18, CD11b-CD18 and CD36.
European journal of immunology - 1 Dec 2002
Nguyen Van Anh, Ebner Susanne, Fürhapter Christina, Romani Nikolaus, Kölle Dieter, Fritsch Peter, Sepp Norbert
Abstract excerpt
DC are sentinels of the immune system. In order to reach the skin, bone-marrow-derived DC precursors need to bind and migrate through microvascular endothelial cells. Binding of DC toprimary endothelial cells of the skin has not been investigated. We therefore determined adhesion of DC at different stages of development to human dermal microvascular endothelial cells (HDMEC). DC were derived from CD34+...
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