Article
Capacity of CD34+ progenitor-derived dendritic cells to distinguish between sensitizers and irritants.
Toxicology letters - 28 Apr 2005
De Smedt Ann C A, Van Den Heuvel Rosette L, Van Tendeloo Vigor F I, Berneman Zwi N, Schoeters Greet E R
Abstract excerpt
In an attempt to develop an in vitro test to identify contact sensitizers, mostly dendritic cells (DCs) derived from monocytes (Mo-DC) have been used. Less is known about the potency of DC derived from CD34+ progenitors (CD34-DC) for in vitro allergen testing. CD34+ progenitor derived DC were exposed to nine well-known allergens (one weak, three moderate and five strong allergens) and two irritants. Surface...
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