Article
IFNGR1 polymorphisms in Thai malaria patients.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2009
Naka Izumi, Patarapotikul Jintana, Hananantachai Hathairad, Tokunaga Katsushi, Tsuchiya Naoyuki, Ohashi Jun
Abstract excerpt
Interferon-gamma (IFN-gamma) has been suggested to play an important role in the pathogenesis of malaria. To examine possible association of the IFN-gamma receptor 1 (IFNGR1) polymorphisms with cerebral malaria, 312 adult patients with Plasmodium falciparum malaria (203 mild and 109 cerebral malaria patients) living in northwest Thailand were genotyped for six single nucleotide polymorphisms (SNPs) including...
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