Article
Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C. elegans vulval induction.
Genes & development - 15 May 2002
Gleason Julie E, Korswagen Hendrik C, Eisenmann David M
Abstract excerpt
During Caenorhabditis elegans vulval development, activation of receptor tyrosine kinase/Ras and Notch signaling pathways causes three vulval precursor cells (VPCs) to adopt induced cell fates. A Wnt signaling pathway also acts in cell fate specification by the VPCs, via regulation of the Hox gen...
Topics
- Adenomatous Polyposis Coli Protein
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Carrier Proteins
- Cell Communication
- Cytoskeletal Proteins
- DNA-Binding Proteins
- Embryonic Induction
- Female
- Gene Expression
- Genes, ras
- Helminth Proteins
- High Mobility Group Proteins
- Homeodomain Proteins
- Hot Temperature
- Insect Proteins
- Intercellular Signaling Peptides and Proteins