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Article

The Caenorhabditis elegans APC-related gene apr-1 is required for epithelial cell migration and Hox gene expression.

Genes & development - 1 Apr 2000

Hoier E F, Mohler W A, Kim S K, Hajnal A

Abstract excerpt

Inactivation of the Caenorhabditis elegans APC-related gene (apr-1) has pointed at two separate functions of apr-1. First, apr-1 is required for the migration of epithelial cells during morphogenesis of the embryo. In this process, APR-1 may act in a Cadherin/alpha-Catenin/beta-Catenin complex as a component of adherens junctions. Second, apr-1 is required for Hox gene expression, most likely by positively...

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PMID: 10766743
PMCID: PMC316495

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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