Article
Conserved mechanism of Wnt signaling function in the specification of vulval precursor fates in C. elegans and C. briggsae.
Developmental biology - 1 Oct 2010
Seetharaman Ashwin, Cumbo Philip, Bojanala Nagagireesh, Gupta Bhagwati P
Abstract excerpt
The C. elegans hermaphrodite vulva serves as a paradigm for understanding how signaling pathways control organ formation. Previous studies have shown that Wnt signaling plays important roles in vulval development. To understand the function and evolution of Wnt signaling in Caenorhabditis nematodes we focused on C. briggsae, a species that is substantially divergent from C. elegans in terms of the evolutionary...
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