The Hox gene lin-39 is required during C. elegans vulval induction to select the outcome of Ras signaling.

doi:10.1242/dev.125.2.181

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Article

The Hox gene lin-39 is required during C. elegans vulval induction to select the outcome of Ras signaling.

Development (Cambridge, England) - 1 Jan 1998

Maloof J N, Kenyon C

Abstract excerpt

The Ras signaling pathway specifies a variety of cell fates in many organisms. However, little is known about the genes that function downstream of the conserved signaling cassette, or what imparts the specificity necessary to cause Ras activation to trigger different responses in different tissu...

Topics

Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Disorders of Sex Development
Embryonic Induction
Female
Gene Expression
Genes, Homeobox
Genes, ras
Homeodomain Proteins
Hot Temperature
Male
Mutation
Signal Transduction
Transcription Factors
Vulva

Source

Open in PubMed

Identifiers

PMID: 9486792
DOI: 10.1242/dev.125.2.181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9486792-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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