Article
The Hox gene lin-39 is required during C. elegans vulval induction to select the outcome of Ras signaling.
Development (Cambridge, England) - 1 Jan 1998
Maloof J N, Kenyon C
Abstract excerpt
The Ras signaling pathway specifies a variety of cell fates in many organisms. However, little is known about the genes that function downstream of the conserved signaling cassette, or what imparts the specificity necessary to cause Ras activation to trigger different responses in different tissues. In C. elegans, activation of the Ras pathway induces cells in the central body region to generate the vulva. Vulval...
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