Protruding vulva mutants identify novel loci and Wnt signaling factors that function during Caenorhabditis elegans vulva development.

doi:10.1093/genetics/156.3.1097

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Article

Protruding vulva mutants identify novel loci and Wnt signaling factors that function during Caenorhabditis elegans vulva development.

Genetics - 1 Nov 2000

Eisenmann D M, Kim S K

Abstract excerpt

The Caenorhabditis elegans vulva develops from the progeny of three vulval precursor cells (VPCs) induced to divide and differentiate by a signal from the somatic gonad. Evolutionarily conserved Ras and Notch extracellular signaling pathways are known to function during this process. To identify...

Topics

Animals
Caenorhabditis elegans
Chromosome Mapping
Disorders of Sex Development
Ethyl Methanesulfonate
Female
Gene Expression Regulation, Developmental
Genes, Helminth
Heterozygote
Male
Mutagenesis
Phenotype
Proto-Oncogene Proteins
Recombination, Genetic
Signal Transduction
Vulva
Wnt Proteins
Zebrafish Proteins

Source

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Identifiers

PMID: 11063687
DOI: 10.1093/genetics/156.3.1097
PMCID: PMC1461321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-11063687-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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