Article
The Pristionchus HOX gene Ppa-lin-39 inhibits programmed cell death to specify the vulva equivalence group and is not required during vulval induction.
Development (Cambridge, England) - 1 Oct 1998
Sommer R J, Eizinger A, Lee K Z, Jungblut B, Bubeck A, Schlak I
Abstract excerpt
In the two nematode species Caenorhabditis elegans and Pristionchus pacificus the vulva equivalence group in the central body region is specified by the Hox gene lin-39. C. elegans lin-39 mutants are vulvaless and the vulval precursor cells fuse with the surrounding hypodermis, whereas in P. pacificus lin-39 mutants the vulval precursor cells die by apoptosis. Mechanistically, LIN-39 might inhibit non-vulval fate...
Topics
- Animals
- Apoptosis
- Base Sequence
- Biological Evolution
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Caspases
- Cloning, Molecular
- Cysteine Endopeptidases
- DNA Primers