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Article

Identification of human mannose binding lectin (MBL) recognition sites for novel inhibitory antibodies.

Hybridoma and hybridomics - 1 Feb 2002

Zhao Hui, Wakamiya Nobutaka, Suzuki Yasuhiko, Hamonko Matthew T, Stahl Gregory L

Abstract excerpt

Mannose binding lectin (MBL) binding initiates activation of the lectin complement pathway. Recent studies from our laboratory have demonstrated that MBL-dependent complement activation mediates cellular injury following oxidative stress in vivo and in vitro. A panel of novel inhibitory monoclonal antibodies (MAbs) against MBL (e.g., MAb 3F8, 2A9, and hMBL1.2) has been developed that inhibit MBL binding and...

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PMID: 11991814
DOI: 10.1089/15368590252917610

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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