Mannan-binding lectin--a soluble pattern recognition molecule.

doi:10.1016/j.molimm.2004.03.015

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Mannan-binding lectin--a soluble pattern recognition molecule.

Molecular immunology - 1 Jun 2004

Gadjeva Mihaela, Takahashi Kazue, Thiel Steffen

Abstract excerpt

The immune system must discriminate between self and non-self. Mannan-binding lectin (MBL) is a recognition molecule able to differentiate between the carbohydrates found on self glycoproteins and the carbohydrate patterns found on infectious non-self surfaces. It exists in a complex with MBL-associated serine proteases (MASPs). When MBL binds to suitable carbohydrate pattern it causes activation of MASPs leading...

Topics

Animals
Genetic Variation
Humans
Immunity, Innate
Infections
Mannose-Binding Lectin
Mannose-Binding Protein-Associated Serine Proteases
Protein Binding
Serine Endopeptidases
Solubility

Source

Open in PubMed

Identifiers

PMID: 15159056
DOI: 10.1016/j.molimm.2004.03.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics