Article
Mannan-binding lectin--a soluble pattern recognition molecule.
Molecular immunology - 1 Jun 2004
Gadjeva Mihaela, Takahashi Kazue, Thiel Steffen
Abstract excerpt
The immune system must discriminate between self and non-self. Mannan-binding lectin (MBL) is a recognition molecule able to differentiate between the carbohydrates found on self glycoproteins and the carbohydrate patterns found on infectious non-self surfaces. It exists in a complex with MBL-associated serine proteases (MASPs). When MBL binds to suitable carbohydrate pattern it causes activation of MASPs leading...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
