Article
The mannose-binding lectin: a prototypic pattern recognition molecule.
Current opinion in immunology - 1 Feb 2006
Takahashi Kazue, Ip Wk Eddie, Michelow Ian C, Ezekowitz R Alan B
Abstract excerpt
The innate immune system is comprised of a sophisticated network of recognition and effector molecules that act together to protect the host in the first minutes or hours of exposure to an infectious challenge. The mannose-binding lectin (MBL) is an evolutionary conserved circulating host defense protein that acts as a broad-spectrum recognition molecule against a wide variety of infectious agents. Target binding...
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