Article
Mannose binding lectin (MBL) in autoimmunity and its role in systemic lupus erythematosus (SLE).
The Journal of the Association of Physicians of India - 1 Nov 2010
Pradhan Vandana, Surve Prathamesh, Ghosh Kanjaksha
Abstract excerpt
Mannose binding lectin (MBL) is an important element of the innate immune system. MBL binding leads to activation and cleavage of C3 and C4 suggesting the role of MBL pathway for opsonization and/ phagocytosis. The role of adaptive immune response in development of pathogenic autoantibodies in various autoimmune diseases is well understood. The link between innate and acquired immunity is helpful for...
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