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Article

Chromosomal regions harboring genes for the work to femur failure in mice.

Functional & integrative genomics - 1 Apr 2002

Li Xinmin, Masinde Godfred, Gu Weikuan, Wergedal Jon, Hamilton-Ulland Melanie, Xu Shizhong, Mohan Subburaman, Baylink David J

Abstract excerpt

The work to failure is defined as the maximum energy bone can absorb before breaking, and therefore is a direct test of the risk of fracture. To determine the genetic loci influencing work to failure, we have performed a high density genome-wide scan in 633 (MRL x SJL) F(2) female mice. Five loci ( P<0.005) with significant effects on work to failure were found on chromosomes 2, 7, 8, 9, and X, which collectively...

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Identifiers

PMID: 11957111
DOI: 10.1007/s10142-001-0045-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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