Article
Quantitative trait loci for tibial bone strength in C57BL/6J and C3H/HeJ inbred strains of mice.
Journal of genetics - 1 Apr 2010
Jiao Feng, Chiu Hank, Jiao Yan, de Rijk Waldemar G, Li Xinmin, Eckstein Eugene C, Beamer Wesley G, Gu Weikuan
Abstract excerpt
Three-point bending technology has been widely used in the measurement of bone strength. Quantitative trait loci (QTLs) for bone strength have been identified using mouse femurs. In this study, we investigate the use of mouse tibiae in identification of QTLs that regulate bone strength. Mouse tibiae were from a F(2) population derived from C57BL/6J (B6) and C3H/HeJ (C3H). Three-point bending was measured using...
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