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Article

Intratumoral genetic heterogeneity in Barrett adenocarcinoma.

American journal of clinical pathology - 1 Apr 2002

Owonikoko Taofeek, Rees Martin, Gabbert Helmut E, Sarbia Mario

Abstract excerpt

In 10 cases of Barrett adenocarcinoma, samples from 8 tumor areas (including superficial and deep from peripheral and central areas) and a regional lymph node metastasis were studied for amplification of c-myc, c-erbB-2, and EGFR. We analyzed loss of heterozygosity (LOH) at 3 loci (APC, MCC, and RB) and 2 anonymous microsatellite markers (D4S1652 and D18S474). We detected c-myc in variable fractions of tissue...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11939730
DOI: 10.1309/6XY8-FMM5-VVCJ-T3N0

Genes

APC
EGFR
MCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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