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Article

Allelotype analysis of oesophageal adenocarcinoma: loss of heterozygosity occurs at multiple sites.

British journal of cancer - 1 Oct 1998

Dolan K, Garde J, Gosney J, Sissons M, Wright T, Kingsnorth A N, Walker S J, Sutton R, Meltzer S J, Field J K

Abstract excerpt

Deletions of tumour-suppressor genes can be detected by loss of heterozygosity (LOH) studies, which were performed on 23 cases of adenocarcinoma of the oesophagus, using 120 microsatellite primers covering all non-acrocentric autosomal chromosome arms. The chromosomal arms most frequently demonstrating LOH were 3p (64% of tumours), 5q (45%), 9p (52%), 11p (61%), 13q (50%), 17p (96%), 17q (55%) and 18q (70%). LOH...

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Source

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Identifiers

PMID: 9764589
DOI: 10.1038/bjc.1998.607
PMCID: PMC2063115

Genes

MSH3
APC
DCC
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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