Allelotype analysis of oesophageal adenocarcinoma: loss of heterozygosity occurs at multiple sites.

doi:10.1038/bjc.1998.607

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Allelotype analysis of oesophageal adenocarcinoma: loss of heterozygosity occurs at multiple sites.

British journal of cancer - 1 Oct 1998

Dolan K, Garde J, Gosney J, Sissons M, Wright T, Kingsnorth A N, Walker S J, Sutton R, Meltzer S J, Field J K

Abstract excerpt

Deletions of tumour-suppressor genes can be detected by loss of heterozygosity (LOH) studies, which were performed on 23 cases of adenocarcinoma of the oesophagus, using 120 microsatellite primers covering all non-acrocentric autosomal chromosome arms. The chromosomal arms most frequently demonst...

Topics

Adenocarcinoma
Aged
Alleles
Esophageal Neoplasms
Female
Gene Deletion
Genotype
Humans
Loss of Heterozygosity
Male
Microsatellite Repeats

Source

Open in PubMed Open full text

Identifiers

PMID: 9764589
DOI: 10.1038/bjc.1998.607
PMCID: PMC2063115

Genes

MSH3
APC
DCC
VHL

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9764589-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.