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Article

Correlation between dysplasia and mutations of six tumor suppressor genes in Barrett's esophagus.

The Annals of thoracic surgery - 1 Oct 2001

Raja S, Finkelstein S D, Baksh F K, Gooding W E, Swalsky P A, Godfrey T E, Buenaventura P O, Luketich J D

Abstract excerpt

BACKGROUND: Barrett's esophagus (BE) may progress to adenocarcinoma through dysplastic progression. Classification of dysplasia in BE has significant interobserver variability. Our objective was to determine whether genetic alterations in BE correlate with degrees of histologic dysplasia. METHODS: Fixed tissue from 37 patients with BE and adenocarcinoma was studied for six tumor suppressor genes. Tissues were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11603424
DOI: 10.1016/s0003-4975(01)03005-3

Genes

APC
DCC
MXI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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