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Article

Histochemical and immunohistochemical evidence of tumor heterogeneity in colorectal cancer.

Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie - 1 Jan 2015

Zlatian Ovidiu Mircea, Comănescu Maria Victoria, Roşu Alexandra Floriana, Roşu Lucica, Cruce Mihai, Găman Alice Elena, Călina Cornelia Daniela, Sfredel Veronica

Abstract excerpt

INTRODUCTION: Intratumoral heterogeneity implies the existence of differences between tumor cells, which can best be shown by histochemical and immunohistochemical techniques. The histological study is a mandatory step in any research aimed at characterizing tumor heterogeneity. Immunohistochemistry (IHC) also plays an important role in the differentiation of tumor types, assessing aggressiveness. MATERIALS AND...

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PMID: 25826503

Genes

KRAS
BCL2
EGFR
MUC1
PCNA
PTEN
MUC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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