Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Translational readthrough of the PDE2 stop codon modulates cAMP levels in Saccharomyces cerevisiae.

Molecular microbiology - 1 Feb 2002

Namy Olivier, Duchateau-Nguyen Guillemette, Rousset Jean-Pierre

Abstract excerpt

The efficiency of translation termination in yeast can vary several 100-fold, depending on the context around the stop codon. We performed a computer analysis designed to identify yeast open reading frames (ORFs) containing a readthrough motif surrounding the termination codon. Eight ORFs were found to display inefficient stop codon recognition, one of which, PDE2, encodes the high-affinity cAMP...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon, Terminator
Share to Cyclic AMP
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Open Reading Frames

Share to Phosphoric Diester Hydrolases

Share to Protein Biosynthesis

Share to Saccharomyces cerevisiae

Source

Identifiers

PMID: 11929521
DOI: 10.1046/j.1365-2958.2002.02770.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Translational readthrough of the PDE2 stop codon modulates cAMP levels in Saccharomyces cerevisiae.PMID 11929521Read ↗

Transcriptome-wide investigation of stop codon readthrough in <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiae.Semantic proximity Read ↗

Genetic basis of hidden phenotypic variation revealed by increased translational readthrough in yeast.Semantic proximity Read ↗

Impact of the six nucleotides downstream of the stop codon on translation termination.Semantic proximity Read ↗

Quantitation of readthrough of termination codons in yeast using a novel gene fusion assay.Semantic proximity Read ↗

Decoding accuracy in eRF1 mutants and its correlation with pleiotropic quantitative traits in yeast.Semantic proximity Read ↗

A novel mutant of the Sup35 protein of Saccharomyces cerevisiae defective in translation termination and in GTPase activity still supports cell viability.Semantic proximity Read ↗

Mutations in yeast Pcf11, a conserved protein essential for mRNA 3' end processing and transcription termination, elicit the Environmental Stress Response.Semantic proximity Read ↗

The pde2 gene of Saccharomyces cerevisiae is allelic to rca1 and encodes a phosphodiesterase which protects the cell from extracellular cAMP.Semantic proximity Read ↗

Fail-safe transcriptional termination for protein-coding genes in S. cerevisiae.Semantic proximity Read ↗

The C-terminus of eRF1 defines a functionally important domain for translation termination in Saccharomyces cerevisiae.Semantic proximity Read ↗

Isolation and characterization of omnipotent suppressors in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.