The pde2 gene of Saccharomyces cerevisiae is allelic to rca1 and encodes a phosphodiesterase which protects the cell from extracellular cAMP.

doi:10.1016/0014-5793(93)81071-7

Back to search

Article

The pde2 gene of Saccharomyces cerevisiae is allelic to rca1 and encodes a phosphodiesterase which protects the cell from extracellular cAMP.

FEBS letters - 5 Jul 1993

Wilson R B, Renault G, Jacquet M, Tatchell K

Abstract excerpt

The high affinity cAMP phosphodiesterase, encoded by PDE2, is an important component of the cAMP-dependent protein kinase signaling system in Saccharomyces cerevisiae. An unexpected phenotype of pde2 mutants is sensitivity to external cAMP. This trait has been found independently for rca1 mutants...

Topics

3',5'-Cyclic-AMP Phosphodiesterases
Alleles
Cyclic AMP
G1 Phase
Genes, Fungal
Saccharomyces cerevisiae
Signal Transduction
Temperature

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.