Article
The C-terminus of eRF1 defines a functionally important domain for translation termination in Saccharomyces cerevisiae.
Molecular microbiology - 1 May 1999
Eurwilaichitr L, Graves F M, Stansfield I, Tuite M F
Abstract excerpt
Translation termination in eukaryotes is mediated by two release factors, eRF1 and eRF3, which interact to form a heterodimer that mediates termination at all three stop codons. By C-terminal deletion analysis of eRF1 from the yeast Saccharomyces cerevisiae, we show that the extreme C-terminus of this 437-amino-acid protein defines a functionally important domain for translation termination. A strain encoding...
Topics
- Amino Acid Sequence
- Animals
- Binding Sites
- Conserved Sequence
- Genes, Suppressor
- Molecular Sequence Data
- Peptide Fragments
- Peptide Termination Factors
- Phenotype
- Protein Biosynthesis
- Recombinant Proteins
- Ribosomes
- Saccharomyces cerevisiae
- Xenopus Proteins
- Xenopus laevis