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Article

The C-terminus of eRF1 defines a functionally important domain for translation termination in Saccharomyces cerevisiae.

Molecular microbiology - 1 May 1999

Eurwilaichitr L, Graves F M, Stansfield I, Tuite M F

Abstract excerpt

Translation termination in eukaryotes is mediated by two release factors, eRF1 and eRF3, which interact to form a heterodimer that mediates termination at all three stop codons. By C-terminal deletion analysis of eRF1 from the yeast Saccharomyces cerevisiae, we show that the extreme C-terminus of this 437-amino-acid protein defines a functionally important domain for translation termination. A strain encoding...

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PMID: 10320572
DOI: 10.1046/j.1365-2958.1999.01346.x

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The C-terminus of eRF1 defines a functionally important domain for translation termination in Saccharomyces cerevisiae.PMID 10320572Read ↗

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