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Article

The genome of Plasmodium falciparum encodes an active delta-aminolevulinic acid dehydratase.

Current genetics - 1 Mar 2002

Sato Shigeharu, Wilson R J M

Abstract excerpt

The enzyme delta-aminolevulinic acid dehydratase (ALAD) catalyses the second reaction in the heme biosynthetic pathway. It has been suggested previously that the malaria parasite Plasmodium falciparum imports this enzyme from the host cell for de novo heme biosynthesis. However, the parasite's genome encodes an orthologue for ALAD. Here we report molecular cloning of a complete cDNA for the parasite's intrinsic...

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Source

Identifiers

PMID: 11919678
DOI: 10.1007/s00294-002-0273-3

Genes

ALAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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