Article
Proteobacteria-like ferrochelatase in the malaria parasite.
Current genetics - 1 Feb 2003
Sato Shigeharu, Wilson R J M
Abstract excerpt
A gene encoding the heme biosynthetic enzyme ferrochelatase (FC) was found in the genomic DNA databases of Plasmodium spp. The predicted amino acid sequence of malarial FC is highly conserved and fairly well conserved by comparison with other orthologues. The FC genes of P. falciparum and P. yoelii are transcribed and the mRNAs are processed to encode polypeptides of the expected amino acid sequence. The cloned...
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