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Article

[delta-Aminolevulinate dehydratase deficiency].

Nihon rinsho. Japanese journal of clinical medicine - 1 Jun 1995

Fujita H, Ishida N, Akagi R

Abstract excerpt

delta-Aminolevulinate dehydratase (ALAD: E. C. 4.2.1.24), the second enzyme in the heme biosynthetic pathway, condenses two moles of delta-aminolevulinic acid to form porphobilinogen. ALAD deficiency is well known to develop signs and symptoms of typical hepatic porphyria, and classified into three categories as follows: (i) ALAD porphyria, a genetic defect of the enzyme, (ii) tyrosinemia type I, a genetic defect...

Topics

Base Sequence
Humans
Hydrolases
Lead Poisoning
Molecular Sequence Data
Mutation
Porphobilinogen Synthase
Porphyrias, Hepatic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7616655

Genes

ALAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7616655-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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