Article
Akt/protein kinase B promotes organ growth in transgenic mice.
Molecular and cellular biology - 1 Apr 2002
Shioi Tetsuo, McMullen Julie R, Kang Peter M, Douglas Pamela S, Obata Toshiyuki, Franke Thomas F, Cantley Lewis C, Izumo Seigo
Abstract excerpt
One of the least-understood areas in biology is the determination of the size of animals and their organs. In Drosophila, components of the insulin receptor phosphoinositide 3-kinase (PI3K) pathway determine body, organ, and cell size. Several biochemical studies have suggested that Akt/protein k...
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