Article
The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo.
Current biology : CB - 19 Mar 2002
Bamba Chisa, Bobinnec Yves, Fukuda Makoto, Nishida Eisuke
Abstract excerpt
The GTPase Ran is known to regulate transport of proteins across the nuclear envelope. Recently, Ran has been shown to promote microtubule polymerization and spindle assembly around chromatin in Xenopus mitotic extracts and to stimulate nuclear envelope assembly in Xenopus or HeLa cell extracts. However, these in vitro findings have not been tested in living cells and do not necessarily describe the generalized...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.