Article
The fission yeast ran GTPase is required for microtubule integrity.
The Journal of cell biology - 27 Nov 2000
Fleig U, Salus S S, Karig I, Sazer S
Abstract excerpt
The microtubule cytoskeleton plays a pivotal role in cytoplasmic organization, cell division, and the correct transmission of genetic information. In a screen designed to identify fission yeast genes required for chromosome segregation, we identified a strain that carries a point mutation in the SpRan GTPase. Ran is an evolutionarily conserved eukaryotic GTPase that directly participates in nucleocytoplasmic...
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