Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Ran GTPase system in fission yeast affects microtubules and cytokinesis in cells that are competent for nucleocytoplasmic protein transport.

Molecular and cellular biology - 1 Dec 2002

Salus Sandra S, Demeter Janos, Sazer Shelley

Abstract excerpt

Misregulation of the evolutionarily conserved GTPase Ran in fission yeast results in defects in several cellular processes in cells that are competent for nucleocytoplasmic protein transport. These results suggest that transport is neither the only nor the primary Ran-dependent process in living cells. The ability of Ran to independently regulate multiple cellular processes in vivo is demonstrated by showing that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Active Transport, Cell Nucleus
Share to Cytoskeleton

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Endopeptidases

Share to Genes, cdc

Share to Microtubules

Share to ran GTP-Binding Protein

Share to Schizosaccharomyces pombe Proteins

Share to Spindle Apparatus

Source

Open in PubMed Open full text

Identifiers

PMID: 12446769
DOI: 10.1128/MCB.22.24.8491-8505.2002
PMCID: PMC139886

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Ran GTPase system in fission yeast affects microtubules and cytokinesis in cells that are competent for nucleocytoplasmic protein transport.PMID 12446769Read ↗

The fission yeast ran GTPase is required for microtubule integrity.Semantic proximity Read ↗

Loss of RanGEF/Pim1 activity abolishes the orchestration of Ran-mediated mitotic cellular events in S. pombe.Semantic proximity Read ↗

Perturbations in the spi1p GTPase cycle of Schizosaccharomyces pombe through its GTPase-activating protein and guanine nucleotide exchange factor components result in similar phenotypic consequences.Semantic proximity Read ↗

A RanBP1 mutation which does not visibly affect nuclear import may reveal additional functions of the ran GTPase system.Semantic proximity Read ↗

The Ran GTPase cycle is required for yeast nuclear pore complex assembly.Semantic proximity Read ↗

Interaction between the small GTPase Ran/Gsp1p and Ntf2p is required for nuclear transport.Semantic proximity Read ↗

Spatial and temporal coordination of mitosis by Ran GTPase.Semantic proximity Read ↗

The interaction between Ran and NTF2 is required for cell cycle progression.Semantic proximity Read ↗

The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo.Semantic proximity Read ↗

Three proteins required for early steps in the protein secretory pathway also affect nuclear envelope structure and cell cycle progression in fission yeast.Semantic proximity Read ↗

Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing.Semantic proximity Read ↗

Plant RanGAPs are localized at the nuclear envelope in interphase and associated with microtubules in mitotic cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.