Article
Dynamic localisation of Ran GTPase during the cell cycle.
BMC cell biology - 18 Sept 2009
Hutchins James R A, Moore William J, Clarke Paul R
Abstract excerpt
BACKGROUND: Ran GTPase has multiple functions during the cell division cycle, including nucleocytoplasmic transport, mitotic spindle assembly and nuclear envelope formation. The activity of Ran is determined by both its guanine nucleotide-bound state and its subcellular localization. RESULTS: Here, we have characterised the localisation and mobility of Ran coupled to green fluorescent protein (GFP) during the...
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