Article
Mitochondrial genetic variants and Alzheimer disease: a case-control study of the T4336C and G5460A variants.
Alzheimer disease and associated disorders - 1 Jan 2000
Edland Steven D, Tobe Vincent O, Rieder Mark J, Bowen James D, McCormick Wayne, Teri Linda, Schellenberg Gerard D, Larson Eric B, Nickerson Deborah A, Kukull Walter A
Abstract excerpt
The T4336C mitochondrial genetic variant was associated with Alzheimer disease in several previous studies. Recent investigations, however, failed to confirm this association. We tested this association in newly diagnosed Alzheimer disease cases and controls of similar age and gender recruited from an established HMO serving Seattle, Washington and surrounding areas. In this, the largest case-control study...
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