Article
Association of the mitochondrial tRNA(A4336G) mutation with Alzheimer's and Parkinson's diseases.
Neuropathology and applied neurobiology - 1 Aug 1997
Egensperger R, Kösel S, Schnopp N M, Mehraein P, Graeber M B
Abstract excerpt
Alzheimer's and Parkinson's diseases (AD, PD) are among the most common neurodegenerative disorders in adults. Both AD and PD have a complex aetiology, and it is widely considered that genetic factors, acting independently or in concert with other genetic and/or environmental factors, modify the...
Topics
- Aged
- Alzheimer Disease
- Apolipoproteins E
- Brain Chemistry
- DNA
- Female
- Gene Frequency
- Genotype
- Humans
- Male
- Mitochondria
- Mutation
- Parkinson Disease
- Polymerase Chain Reaction
- Polymorphism, Genetic
- RNA, Transfer
- alpha 1-Antichymotrypsin
