Article
Mitochondrial DNA A4336G mutation in Alzheimer's and Parkinson's diseases.
European neurology - 1 Jan 2002
García-Lozano José Raúl, Mir Pablo, Alberca Román, Aguilera Isabel, Gil Néciga Eulogio, Fernández-López Olga, Cayuela Aurelio, Núñez-Roldan Antonio
Abstract excerpt
OBJECTIVES: To determine whether the mitochondrial DNA (mtDNA) A4336G mutation represents a risk factor for Spanish patients with both Alzheimer's disease (AD) and Parkinson's disease (PD). MATERIAL AND METHODS: One hundred and sixty-one AD and 106 PD unrelated patients were included in the study. Seventy-eight age-matched and 144 randomly chosen healthy subjects served as controls. The frequency of the A4336G...
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