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Article

Enhanced T cell responses contribute to the genetic predisposition of CD8-mediated spontaneous autoimmunity.

European journal of immunology - 1 Mar 2002

Garza Kristine M, McKall-Faienza Kim J, Otheki Tashiaki, Zakarian Arsen, Odermatt Bernhard, Ohashi Pamela S

Abstract excerpt

A number of factors have been demonstrated to influence the induction of pathogenic autoimmune responses, including the loss of regulatory T cells. To assess the contribution of regulatory T cells in CD8(+) T cell-mediated autoimmunity, RIP-gp/P14 double-transgenic mice expressing the lymphocytic choriomeningitis virus (LCMV) glycoprotein (gp) on pancreatic beta-islet cells, together with T cells expressing an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11870633
DOI: 10.1002/1521-4141(200203)32:3<885::AID-IMMU885>3.0.CO;2-E

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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