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Article

Twinfilin, a molecular mailman for actin monomers.

Journal of cell science - 1 Mar 2002

Palmgren Sandra, Vartiainen Maria, Lappalainen Pekka

Abstract excerpt

Twinfilin is a ubiquitous actin-monomer-binding protein that is composed of two ADF-homology domains. It forms a 1:1 complex with ADP-actin-monomers, inhibits nucleotide exchange on actin monomers and prevents assembly of the monomer into filaments. The two ADF-H domains in twinfilin probably have 3D structures similar to those of the ADF/cofilin proteins and overlapping actin-binding sites. Twinfilin also...

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Identifiers

PMID: 11870207
DOI: 10.1242/jcs.115.5.881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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