Article
Cofilin/ADF is required for cell motility during Drosophila ovary development and oogenesis.
Nature cell biology - 1 Feb 2001
Chen J, Godt D, Gunsalus K, Kiss I, Goldberg M, Laski F A
Abstract excerpt
The driving force behind cell motility is the actin cytoskeleton. Filopodia and lamellipodia are formed by the polymerization and extension of actin filaments towards the cell membrane. This polymerization at the barbed end of the filament is balanced by depolymerization at the pointed end, recyc...
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