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Article

Identification of yeast cofilin residues specific for actin monomer and PIP2 binding.

Biochemistry - 25 Dec 2001

Ojala P J, Paavilainen V, Lappalainen P

Abstract excerpt

Cofilin/ADF is a ubiquitous actin-binding protein that is important for rapid actin dynamics in vivo. The long alpha-helix (helix 3 in yeast cofilin) forms the most highly conserved region in cofilin/ADF proteins, and residues in the NH2-terminal half of this alpha-helix have been shown to be essential for actin binding in cofilin/ADF. Recent studies also suggested that the basic residues in the COOH-terminal...

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PMID: 11747431
DOI: 10.1021/bi0117697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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