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Article

Interactions with PIP2, ADP-actin monomers, and capping protein regulate the activity and localization of yeast twinfilin.

The Journal of cell biology - 15 Oct 2001

Palmgren S, Ojala P J, Wear M A, Cooper J A, Lappalainen P

Abstract excerpt

Twinfilin is a ubiquitous actin monomer-binding protein that regulates actin filament turnover in yeast and mammalian cells. To elucidate the mechanism by which twinfilin contributes to actin filament dynamics, we carried out an analysis of yeast twinfilin, and we show here that twinfilin is an abundant protein that localizes to cortical actin patches in wild-type yeast cells. Native gel assays demonstrate that...

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Identifiers

PMID: 11604420
DOI: 10.1083/jcb.200106157
PMCID: PMC2198831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interactions with PIP2, ADP-actin monomers, and capping protein regulate the activity and localization of yeast twinfilin.PMID 11604420Read ↗

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