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Mutations in twinstar, a Drosophila gene encoding a cofilin/ADF homologue, result in defects in centrosome migration and cytokinesis.

The Journal of cell biology - 1 Dec 1995

Gunsalus K C, Bonaccorsi S, Williams E, Verni F, Gatti M, Goldberg M L

Abstract excerpt

We describe the phenotypic and molecular characterization of twinstar (tsr), an essential gene in Drosophila melanogaster. Two P-element induced alleles of tsr (tsr1 and tsr2) result in late larval or pupal lethality. Cytological examination of actively dividing tissues in these mutants reveals d...

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Base Sequence
Amino Acid Sequence
DNA
Cloning, Molecular
Chromosome Mapping
Cell Division

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Drosophila melanogaster

Drosophila Proteins

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PMID: 8522587
DOI: 10.1083/jcb.131.5.1243
PMCID: PMC2120640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8522587-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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