Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in twinstar, a Drosophila gene encoding a cofilin/ADF homologue, result in defects in centrosome migration and cytokinesis.

The Journal of cell biology - 1 Dec 1995

Gunsalus K C, Bonaccorsi S, Williams E, Verni F, Gatti M, Goldberg M L

Abstract excerpt

We describe the phenotypic and molecular characterization of twinstar (tsr), an essential gene in Drosophila melanogaster. Two P-element induced alleles of tsr (tsr1 and tsr2) result in late larval or pupal lethality. Cytological examination of actively dividing tissues in these mutants reveals defects in cytokinesis in both mitotic (larval neuroblast) and meiotic (larval testis) cells. In addition, mutant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Division

Share to Chromosome Mapping

Share to Cloning, Molecular

Share to Drosophila melanogaster

Share to Drosophila Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 8522587
DOI: 10.1083/jcb.131.5.1243
PMCID: PMC2120640

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in twinstar, a Drosophila gene encoding a cofilin/ADF homologue, result in defects in centrosome migration and cytokinesis.PMID 8522587Read ↗

Cofilin/ADF is required for cell motility during Drosophila ovary development and oogenesis.Semantic proximity Read ↗

Cooperative interactions between the central spindle and the contractile ring during Drosophila cytokinesis.Semantic proximity Read ↗

Tombola, a tesmin/TSO1-family protein, regulates transcriptional activation in the Drosophila male germline and physically interacts with always early.Semantic proximity Read ↗

Twinstar, the Drosophila homolog of cofilin/ADF, is required for planar cell polarity patterning.Semantic proximity Read ↗

Cofilin/ADF is required for retinal elongation and morphogenesis of the Drosophila rhabdomere.Semantic proximity Read ↗

Twinfilin, a molecular mailman for actin monomers.Semantic proximity Read ↗

Drosophila Doublefault protein coordinates multiple events during male meiosis by controlling mRNA translation.Semantic proximity Read ↗

Drosophila male meiosis as a model system for the study of cytokinesis in animal cells.Semantic proximity Read ↗

Molecular dissection of cytokinesis by RNA interference in Drosophila cultured cells.Semantic proximity Read ↗

Transcriptional and post-transcriptional control mechanisms coordinate the onset of spermatid differentiation with meiosis I in Drosophila.Semantic proximity Read ↗

Insight into actin organization and function in cytokinesis from analysis of fission yeast mutants.Semantic proximity Read ↗

Transcriptional activation in Drosophila spermatogenesis involves the mutually dependent function of aly and a novel meiotic arrest gene cookie monster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.