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Article

Ligand-induced activation of a formin-NPF pair leads to collaborative actin nucleation.

The Journal of cell biology - 13 May 2013

Graziano Brian R, Jonasson Erin M, Pullen Jessica G, Gould Christopher J, Goode Bruce L

Abstract excerpt

Formins associate with other nucleators and nucleation-promoting factors (NPFs) to stimulate collaborative actin assembly, but the mechanisms regulating these interactions have been unclear. Yeast Bud6 has an established role as an NPF for the formin Bni1, but whether it also directly regulates the formin Bnr1 has remained enigmatic. In this paper, we analyzed NPF-impaired alleles of bud6 in a bni1Δ background...

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Identifiers

PMID: 23671312
DOI: 10.1083/jcb.201212059
PMCID: PMC3653363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ligand-induced activation of a formin-NPF pair leads to collaborative actin nucleation.PMID 23671312Read ↗

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