Article
Tbx1: Transcriptional and Developmental Functions.
Current topics in developmental biology - 1 Jan 2017
Baldini A, Fulcoli F G, Illingworth E
Abstract excerpt
Recent data have paved the way to mechanistic studies into the role of Tbx1 during development. Tbx1 is haploinsufficient and is involved in an important genetic disorder. The gene encodes a T-box transcription factor that is expressed from approximately E7.5 in mouse embryos and continues to be expressed in a highly dynamic manner. It is neither a strong transcriptional activator nor a strong repressor, but it...
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