Article
Differential DNA binding and transcription modulation by three T-box proteins, T, TBX1 and TBX2.
Gene - 27 Nov 2000
Sinha S, Abraham S, Gronostajski R M, Campbell C E
Abstract excerpt
T-box genes encode a family of phylogenetically conserved DNA-binding proteins that regulate gene expression during embryogenesis. While the developmental importance of many T-box genes has been well documented, little is known about how family members differ in their DNA binding properties and ability to modulate transcription. Here we show that although TBX1, TBX2 and the Xenopus T protein (Xbra) share only...
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